Crystallization

Single Crystal Structure Elucidation

Center for Pharma Crystallization

J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512

Are you facing challenges getting reliable single crystal structures of APIs or intermediate compounds?

You can get professional help from our leading crystallization expert with …

CfPC at J-STAR Research

CfPC at J-STAR Research

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512

See how the Center for Pharma Crystallization (CfPC) at J-STAR Research is effectively supporting new drug development programs: https://www.jstar-research.com/contract-rd-services/crystallization-rd/…

Preformulation Strategy – Inception to Completion

 
Drug discovery is an exceedingly complex process. Discovering a new chemical entity is in itself a huge accomplishment, which is often possible only after almost two decades of hard experimental work as well as advanced simulation efforts. Therefore, the next …

A Challenging Path to Controlled Nano-API Crystallization and Isolation


Don Kientzler

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512

Abstract

Controlled crystallization of an API in submicron size was enabled based on an accurate solubility profile and a growth inhibition property via semi-continuous …

Addressing Bottleneck Problems in Crystallization R&D for New Drug Development

Jian Wang

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512
Abstract

Diverse crystallization challenges encountered by CfPC (Center for Pharma Crystallization) and our clients will be analyzed systematically to provide insights into main bottleneck …

Pharmaceutical Crystallization Support by Computational Approaches

Yuriy A. Abramov

yuriy.abramov@xtalpi.com
XtalPi Inc, Cambridge MA, USA.
Abstract

Given challenges facing the pharmaceutical industry, an accelerated Drug Development greatly benefits from guidance provided by computational methods.1 This presentation will focus on computational support of the following important tasks …

2020 Pharmaceutical Crystallization Summit Report

Crystallization technologies are bridges between drug substances (DS) and drug products (DP) enabling consistent and robust safety and efficacy profiles of small molecule based medicines. In an effort to fully utilize existing tools and develop better new method-logies for solving …

Computation Assisted Solvent Selection in Crystal Form Investigation


Dr. Shanming Kuang

Center for Pharma Crystallization, J-STAR Research Inc
6 Cedar Drive, Cranbury, New Jersey 08512
shanming.kuang@jstar-research.com

Abstract

Rational selection of solvents plays a critical role in solid form screening and production. On the one hand, a variety of …

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