Process Simplification Series No. 7: Lipid-Based Formulations of Liquid-filled Capsules for Poorly soluble Drugs

Process Simplification Series No. 7: Lipid-Based Formulations of Liquid-filled Capsules for Poorly soluble Drugs to Stay Away from Potential Manufacturing Issues of Oral Solid Dosages

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For a drug substance administered via oral route, it should possess adequately aqueous solubility before passes through the gastrointestinal tract to complete the absorption, and then enters the blood steams for the pharmacological actions. Hence the solubility of a drug substance is one of the most important physicochemical properties to determine the drug’s fate to be developed the drug product for clinical applications.

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