Founded in 1996 J-STAR Research, Inc. is a contract process R&D and cGMP manufacturing organization serving as an outsourcing partner for the pharmaceutical and biotechnology industry.
Particle Engineering & Co-Processing CRO services including dry & wet milling, growth & nucleation dominated…
Our services in catalysis reaction development are differentiated through our integrated approach in the overall…
J-STAR Research, Inc. offers pharmaceutical Contract Research & Development services including Process Chemistry, Analytical R&D,…
| Impurity Characterization | # |
|---|---|
| NMR systems (1 x 300 MHz, 2 x 400 MHz, 1 x 500 MHz) • Varian 500 with 3 mm inverse probe for sub-milligram quantities new in 2019 • New – Varian proton/fluorine cryoprobe at 500 MHz • Bruker 400 multinuclear probe for hetero nuclei NMR (19F, 31P, 15N, etc.) • NMR Characterization of less than 1 mg samples and mixed fractions | 4 |
| HPLC/UPLC systems • Obtain analytical verification and purity of isolate(s) | >30 |
| CAD units • Obtain analytical verification and purity of isolate(s) | 4 |
| HPLC/UPLC-MS • Use MS-MS fragmentation data to assign whole or parts of impurity structure | 7 |
| GC-MS • Use MS-MS fragmentation data to assign whole or parts of impurity structure | 3 |
| UPLC-Orbitrap MS (accurate mass) new in 2018 • Obtain parent and fragment formula data to assign whole or parts of impurity structure | 1 |
| Single Crystal X-ray Diffractometer new in 2018 • Bruker D8 Quest • Establish unambiguous structure and absolute stereochemistry | 1 |
| Adjunctive Solid State Support | # |
|---|---|
| XRPDs • PANalytical Empyrean Diffractometer [High Throughput] new in 2019 • Bruker D2 Phaser • Rigaku MiniFlex • PANalytical | 4 |
| SEM • Nanoimages SNE-4500M with Xflash 630M light element SD detector and MCM-100 Sputter coater | 1 |
| TGA/DVS systems | multiple |
| DSC systems | multiple |
